{"id":1454,"date":"2025-10-16T13:27:46","date_gmt":"2025-10-16T06:27:46","guid":{"rendered":"https:\/\/amigos.vn\/?p=1454"},"modified":"2026-02-02T13:47:38","modified_gmt":"2026-02-02T06:47:38","slug":"complete-additive-solutions-for-niclosamide-and-niclosamide-olamine-formulations","status":"publish","type":"post","link":"https:\/\/amigos.vn\/en\/complete-additive-solutions-for-niclosamide-and-niclosamide-olamine-formulations\/","title":{"rendered":"Complete Additive Solutions for Niclosamide and Niclosamide-olamine Formulations"},"content":{"rendered":"<p><strong>\u00a0 \u00a0 <span style=\"color: #3366ff;\">\u00a0Introduction to Niclosamide and Niclosamide-olamine<\/span><\/strong><br \/>\n\u00a0 \u00a0 Niclosamide is a highly effective active ingredient used to control the golden apple snail (<em>Pomacea canaliculata<\/em>) and is widely applied in Vietnamese agriculture. Niclosamide-olamine, the salt form of Niclosamide, offers better water solubility and easier handling during formulation.<\/p>\n<p><strong>\u00a0 \u00a0 \u00a0<span style=\"color: #3366ff;\">Important Conversion Factor<\/span><\/strong><br \/>\nAccording to FAO standards, the niclosamide content in technical materials is as follows:<\/p>\n<ul>\n<li><strong>Niclosamide (TC):<\/strong>\u00a0minimum 960 g\/kg<\/li>\n<li><strong>Niclosamide-olamine (TK):<\/strong>\u00a0800 g niclosamide\/kg, equivalent to 949 g niclosamide-olamine\/kg<\/li>\n<\/ul>\n<p>\u00a0 \u00a0 \u00a0This means that <strong>1 kg of Niclosamide-olamine contains approximately 0.843 kg of Niclosamide (800\/949)<\/strong>. This conversion factor must be accurately calculated when switching between raw material forms to ensure the active ingredient content meets registration requirements.<\/p>\n<p><span style=\"color: #3366ff;\"><strong>\u00a0 \u00a0 \u00a0Challenges in Niclosamide Formulation<\/strong><\/span><br \/>\n\u00a0 \u00a0 \u00a0Formulating Niclosamide-olamine products faces three key technical challenges:<\/p>\n<ul>\n<li style=\"list-style-type: none;\">\n<ul>\n<li><strong>Precipitation in hard water:<\/strong> Niclosamide-olamine tends to precipitate when diluted in high-hardness water (standard hard water D according to\u00a0<strong>TCVN 8050:2016<\/strong>), which reduces spraying efficiency, as suspensibility is often low and difficult to meet the minimum requirement of\u00a0<strong>60%<\/strong>\u00a0as specified by regulations.<\/li>\n<li><strong>Color change: <\/strong>When unsuitable adjuvants are used, in addition to precipitation issues, the product also undergoes rapid color change.<\/li>\n<li><strong>Suspensibility: <\/strong>Maintaining\u00a0<strong>suspensibility above 80%<\/strong>, minimizing sedimentation and phase separation, and ensuring a homogeneous spray solution over an extended period to optimize spraying performance remains a major challenge from an adjuvant perspective.<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-2310\" src=\"https:\/\/amigos.vn\/wp-content\/uploads\/2025\/10\/Niclosamide-1-Eng-Ver.png\" alt=\"\" width=\"350\" height=\"525\" srcset=\"https:\/\/amigos.vn\/wp-content\/uploads\/2025\/10\/Niclosamide-1-Eng-Ver.png 1024w, https:\/\/amigos.vn\/wp-content\/uploads\/2025\/10\/Niclosamide-1-Eng-Ver-200x300.png 200w, https:\/\/amigos.vn\/wp-content\/uploads\/2025\/10\/Niclosamide-1-Eng-Ver-683x1024.png 683w, https:\/\/amigos.vn\/wp-content\/uploads\/2025\/10\/Niclosamide-1-Eng-Ver-768x1152.png 768w, https:\/\/amigos.vn\/wp-content\/uploads\/2025\/10\/Niclosamide-1-Eng-Ver-600x900.png 600w\" sizes=\"auto, (max-width: 350px) 100vw, 350px\" \/><\/p>\n<p><strong>\u00a0 \u00a0 \u00a0<span style=\"color: #3366ff;\">Optimized Solution for WP (Wettable Powder)<\/span><\/strong><br \/>\n<strong>\u00a0 \u00a0<\/strong><strong>Tergos\u00ae 9014 and Tergos\u00ae 9018 EXP are two specialized adjuvants developed to fully address the above challenges:<\/strong><\/p>\n<p style=\"padding-left: 40px;\">\u2713\u00a0<strong>Rapid wetting:<\/strong>\u00a0Enables the powder to disperse evenly immediately upon contact with water<br \/>\n\u2713\u00a0<strong>High suspensibility:<\/strong>\u00a0Maintains\u00a0<strong>&gt;95%<\/strong>\u00a0over an extended period (when using\u00a0<strong>Tergos\u00ae 9018 EXP at 6%<\/strong>\u00a0in a\u00a0<strong>Niclosamide 700 g\/kg WP<\/strong>\u00a0formulation)<br \/>\n\u2713\u00a0<strong>Cost optimization:<\/strong>\u00a0No need to combine with additional surfactants<br \/>\n\u2713\u00a0<strong>Color stability:<\/strong>\u00a0Keeps the product color stable throughout the storage period<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-1604\" src=\"https:\/\/amigos.vn\/wp-content\/uploads\/2025\/10\/Niclosamide-test.jpg\" alt=\"\" width=\"350\" height=\"329\" srcset=\"https:\/\/amigos.vn\/wp-content\/uploads\/2025\/10\/Niclosamide-test.jpg 1056w, https:\/\/amigos.vn\/wp-content\/uploads\/2025\/10\/Niclosamide-test-300x282.jpg 300w, https:\/\/amigos.vn\/wp-content\/uploads\/2025\/10\/Niclosamide-test-1024x962.jpg 1024w, https:\/\/amigos.vn\/wp-content\/uploads\/2025\/10\/Niclosamide-test-768x721.jpg 768w, https:\/\/amigos.vn\/wp-content\/uploads\/2025\/10\/Niclosamide-test-600x564.jpg 600w\" sizes=\"auto, (max-width: 350px) 100vw, 350px\" \/><\/p>\n<p><span style=\"color: #3366ff;\"><strong>\u00a0 \u00a0 \u00a0Expanding into Advanced Formulations<\/strong><\/span><br \/>\n\u00a0 \u00a0Although Niclosamide and Niclosamide-olamine are primarily registered in WP form, the market is shifting toward modern formulations such as\u00a0<strong>SC (suspension concentrate), EC (emulsifiable concentrate), and WDG (water dispersible granules)<\/strong>. These provide greater convenience and effectiveness for farmers.<\/p>\n<p>\u00a0 \u00a0Amigos is proud to offer a <strong>complete portfolio of additive solutions<\/strong>\u00a0for all potential Niclosamide formulations, enabling manufacturers to diversify product lines and capture new market opportunities.<\/p>\n<p><strong>\u00a0 \u00a0 \u00a0<span style=\"color: #3366ff;\">Comparison of Niclosamide Additive Solutions<\/span><\/strong><\/p>\n<table style=\"width: 100%; border-collapse: collapse; border-style: double; border-color: #f00e0e; height: 456px;\" border=\"1\">\n<tbody>\n<tr style=\"height: 56px;\">\n<td style=\"width: 16.7335%; height: 56px; text-align: center; background-color: #386df2;\" width=\"140\">\n<p><span style=\"color: #000000;\"><strong><em>Product<\/em><\/strong><\/span><\/p>\n<\/td>\n<td style=\"width: 19.7395%; height: 56px; text-align: center; background-color: #386df2;\">\n<p><span style=\"color: #000000;\"><strong>Main Components<\/strong><\/span><\/p>\n<\/td>\n<td style=\"width: 16.1323%; height: 56px; text-align: center; background-color: #386df2;\">\n<p><span style=\"color: #000000;\"><strong>Appearance<\/strong><\/span><\/p>\n<\/td>\n<td style=\"width: 9.81969%; height: 56px; text-align: center; background-color: #386df2;\">\n<p><span style=\"color: #000000;\"><strong>pH (1%)<\/strong><\/span><\/p>\n<\/td>\n<td style=\"width: 11.7234%; height: 56px; text-align: center; background-color: #386df2;\">\n<p><span style=\"color: #000000;\"><strong>Solubility<\/strong><\/span><\/p>\n<\/td>\n<td style=\"width: 25.7515%; height: 56px; text-align: center; background-color: #386df2;\" width=\"173\">\n<p><span style=\"color: #000000;\"><strong>Reference Formulation<\/strong><\/span><\/p>\n<\/td>\n<\/tr>\n<tr style=\"height: 80px;\">\n<td style=\"width: 16.7335%; height: 80px; background-color: #e8b548;\" width=\"140\">\n<p><span style=\"color: #000000;\"><strong><em>Tergos\u00ae 9014<\/em><\/strong><\/span><\/p>\n<\/td>\n<td style=\"width: 19.7395%; height: 80px;\">\n<p>Surfactant blend with alkyl sulphate group<\/p>\n<\/td>\n<td style=\"width: 16.1323%; height: 80px;\">\n<p>Fine white powder<\/p>\n<\/td>\n<td style=\"width: 9.81969%; text-align: center; height: 80px;\">\n<p>6 \u2013 8<\/p>\n<\/td>\n<td style=\"width: 11.7234%; height: 80px;\">\n<p>Water-soluble<\/p>\n<\/td>\n<td style=\"width: 25.7515%; height: 80px;\" width=\"173\">\n<p>Niclosamide-olamine 860 g\/kg WP<\/p>\n<\/td>\n<\/tr>\n<tr style=\"height: 80px;\">\n<td style=\"width: 16.7335%; height: 80px; background-color: #e8b548;\" width=\"140\">\n<p><span style=\"color: #000000;\"><strong><em>Tergos\u00ae 9016<\/em><\/strong><\/span><\/p>\n<\/td>\n<td style=\"width: 19.7395%; height: 80px;\">\n<p>Surfactant polymer blend with polysaccharide<\/p>\n<\/td>\n<td style=\"width: 16.1323%; height: 80px;\">\n<p>Fine white powder<\/p>\n<\/td>\n<td style=\"width: 9.81969%; text-align: center; height: 80px;\">\n<p>10 \u2013 12<\/p>\n<\/td>\n<td style=\"width: 11.7234%; height: 80px;\">\n<p>Water-soluble<\/p>\n<\/td>\n<td style=\"width: 25.7515%; height: 80px;\" width=\"173\">\n<p>Niclosamide 700 \u2013 750 g\/kg WP<\/p>\n<\/td>\n<\/tr>\n<tr style=\"height: 80px;\">\n<td style=\"width: 16.7335%; height: 80px; background-color: #e8b548;\" width=\"140\">\n<p><span style=\"color: #000000;\"><strong><em>Tergos\u00ae DG 8153<\/em><\/strong><\/span><\/p>\n<\/td>\n<td style=\"width: 19.7395%; height: 80px;\">\n<p>Polycarboxylate-based surfactant blend<\/p>\n<\/td>\n<td style=\"width: 16.1323%; height: 80px;\">\n<p>Fine powder<\/p>\n<\/td>\n<td style=\"width: 9.81969%; text-align: center; height: 80px;\">\n<p>\u2013<\/p>\n<\/td>\n<td style=\"width: 11.7234%; height: 80px;\">\n<p>Water-soluble<\/p>\n<\/td>\n<td style=\"width: 25.7515%; height: 80px;\" width=\"173\">\n<p>Niclosamide-olamine 830 g\/kg WG<\/p>\n<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 16.7335%; background-color: #e8b548;\">\n<p><span style=\"color: #000000;\"><strong><em>Tergos\u00ae 9018 EXP<\/em><\/strong><\/span><\/p>\n<\/td>\n<td style=\"width: 19.7395%;\">\n<p>Polymer surfactant blend<\/p>\n<\/td>\n<td style=\"width: 16.1323%;\">\n<p>Fine white powder<\/p>\n<\/td>\n<td style=\"width: 9.81969%; text-align: center;\">\n<p>\u2013<\/p>\n<\/td>\n<td style=\"width: 11.7234%;\">\n<p>Water-soluble<\/p>\n<\/td>\n<td style=\"width: 25.7515%;\">\n<p>Niclosamide 700 &#8211; 750 g\/kg WP<\/p>\n<\/td>\n<\/tr>\n<tr style=\"height: 80px;\">\n<td style=\"width: 16.7335%; height: 80px; background-color: #e8b548;\" width=\"140\">\n<p><span style=\"color: #000000;\"><strong><em>Ericol\u2122 NIC-C<\/em><\/strong><\/span><\/p>\n<\/td>\n<td style=\"width: 19.7395%; height: 80px;\">\n<p>Polyoxyethylene alkyl ether surfactant blend<\/p>\n<\/td>\n<td style=\"width: 16.1323%; height: 80px;\">\n<p>Light yellow liquid<\/p>\n<\/td>\n<td style=\"width: 9.81969%; height: 80px; text-align: center;\">\n<p>\u2013<\/p>\n<\/td>\n<td style=\"width: 11.7234%; height: 80px; text-align: center;\">\n<p>\u2013<\/p>\n<\/td>\n<td style=\"width: 25.7515%; height: 80px;\" width=\"173\">\n<p>Niclosamide 250 g\/L EC<\/p>\n<\/td>\n<\/tr>\n<tr style=\"height: 80px;\">\n<td style=\"width: 16.7335%; height: 80px; background-color: #e8b548;\" width=\"140\">\n<p><span style=\"color: #000000;\"><strong><em>Ericol\u2122 NIC-O<\/em><\/strong><\/span><\/p>\n<\/td>\n<td style=\"width: 19.7395%; height: 80px;\">\n<p>Water-soluble nonionic polymer surfactant<\/p>\n<\/td>\n<td style=\"width: 16.1323%; height: 80px;\">\n<p>Clear yellow solution<\/p>\n<\/td>\n<td style=\"width: 9.81969%; text-align: center; height: 80px;\">\n<p>3 \u2013 6 (direct)<\/p>\n<\/td>\n<td style=\"width: 11.7234%; height: 80px;\">\n<p>Water-soluble<\/p>\n<\/td>\n<td style=\"width: 25.7515%; height: 80px;\" width=\"173\">\n<p>Niclosamide-olamine 500 g\/L SC<\/p>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p><iframe loading=\"lazy\" src=\"\/\/www.youtube.com\/embed\/U6xK_2TMv24?si=OwMzKymFUVTbFK-4\" width=\"560\" height=\"314\" allowfullscreen=\"allowfullscreen\"><\/iframe><\/p>\n<p><strong>\u00a0 \u00a0 <span style=\"color: #3366ff;\">\u00a0Conclusion<\/span><\/strong><br \/>\n\u00a0 \u00a0 \u00a0With a comprehensive range of <strong>Tergos\u00ae and Ericol\u2122 additive solutions<\/strong>, crop protection manufacturers can:<\/p>\n<ul>\n<li style=\"list-style-type: none;\">\n<ul style=\"list-style-type: disc;\">\n<li>Completely resolve formulation challenges in Niclosamide production<\/li>\n<li>Optimize production costs<\/li>\n<li>Expand product portfolios with multiple formulation types<\/li>\n<li>Enhance product quality and competitiveness in the market<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<p style=\"text-align: center;\"><strong>For detailed consultation on formulations and trial samples, please contact our technical team.<\/strong><\/p>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u00a0 \u00a0 \u00a0Introduction to Niclosamide and Niclosamide-olamine \u00a0 \u00a0 Niclosamide is a highly effective active ingredient used to control the golden apple snail (Pomacea canaliculata) and is widely applied in Vietnamese agriculture. Niclosamide-olamine, the salt form of Niclosamide, offers better water solubility and easier handling during formulation. \u00a0 \u00a0 \u00a0Important Conversion Factor According to FAO [&hellip;]<\/p>\n","protected":false},"author":4,"featured_media":1604,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[64,1],"tags":[],"class_list":["post-1454","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-news","category-rd"],"acf":[],"_links":{"self":[{"href":"https:\/\/amigos.vn\/en\/wp-json\/wp\/v2\/posts\/1454","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/amigos.vn\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/amigos.vn\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/amigos.vn\/en\/wp-json\/wp\/v2\/users\/4"}],"replies":[{"embeddable":true,"href":"https:\/\/amigos.vn\/en\/wp-json\/wp\/v2\/comments?post=1454"}],"version-history":[{"count":6,"href":"https:\/\/amigos.vn\/en\/wp-json\/wp\/v2\/posts\/1454\/revisions"}],"predecessor-version":[{"id":2335,"href":"https:\/\/amigos.vn\/en\/wp-json\/wp\/v2\/posts\/1454\/revisions\/2335"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/amigos.vn\/en\/wp-json\/wp\/v2\/media\/1604"}],"wp:attachment":[{"href":"https:\/\/amigos.vn\/en\/wp-json\/wp\/v2\/media?parent=1454"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/amigos.vn\/en\/wp-json\/wp\/v2\/categories?post=1454"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/amigos.vn\/en\/wp-json\/wp\/v2\/tags?post=1454"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}